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Creatine and the Brain
Creatine is one of the most popular supplements in the fitness world, but its benefits go far beyond muscle growth and physical performance. For biohackers, creatine is a tool that can enhance brain function, protect against neurological diseases, and optimize cognitive performance.
Creatine is a natural compound that the body produces from the amino acids glycine, arginine, and methionine. It is primarily stored in the muscles as creatine phosphate and serves as a rapid energy source by helping regenerate ATP (adenosine triphosphate) – the body’s main energy currency.
But just like muscles, the brain is an energy-demanding machine. Creatine plays a crucial role in maintaining optimal brain function, especially during stressful or high-energy-demanding situations.
Studies have shown that creatine supplementation can improve memory, reaction time, and mental clarity, especially in situations where the brain is under high stress – such as sleep deprivation or intense mental work.
Creatine has been found to protect brain cells from oxidative stress and excitotoxic damage. This means it may reduce the risk of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS.
Creatine can reduce mental fatigue by optimizing energy utilization in the brain. Studies also suggest that creatine may act as a natural antidepressant by influencing the serotonin system and reducing brain inflammation.
Biohackers are obsessed with mitochondria – and for good reason! These tiny powerhouses in our cells are key to energy production and long-term health. Creatine supports mitochondrial function by improving energy flow, which can lead to better endurance, sharper focus, and long-term brain health.
For cognitive benefits, a dose of 3–5 grams of creatine monohydrate per day is recommended. Creatine can be taken at any time of the day and is best absorbed when consumed with food.
For those following a ketogenic or carnivore diet, where dietary creatine intake may already be higher, supplementation can still provide an extra boost.
Creatine is more than just a muscle-building supplement – it’s a biohack for the brain. By enhancing energy production, protecting nerve cells, and optimizing cognitive performance, creatine is one of the simplest and most effective investments you can make for your brain health.
